James Harden had 16 points and 13 assists but was just 5 of 16 from the field and missed all six of his 3-pointers as LA was eliminated in the first round for the second consecutive season.
Irving, Doncic's co-star added at the trade deadline last year for the kind of playoff run the Mavs hope they just started, gave Dallas its biggest lead with a flashy four-point play when he hit a leaning 3-pointer as he was bumped by P.J. Tucker and made the free throw for a 106-82 lead.
The Clippers answered with an 11-2 run to get within 13 but never seriously threatened a big comeback in the final minutes.
The Mavs broke a 52-52 halftime tie by outscoring the Clippers 35-20 in the third quarter — the same quarter that fueled the Game 5 win in Los Angeles for a chance to clinch — and pushed the lead to 20 early in the fourth.
Doncic, who also has dealt with illness in addition to a sore knee, started 0 of 7 from 3-point range to drop below 25% for the series but made his first try of the second half to start the third-quarter surge.
The NBA scoring champion was 9 of 26 from the field and just 1 of 10 from 3 while going 9 of 11 on free throws. Irving was 10 of 13 from the field after halftime.
Norman Powell scored 20 for the Clippers, and Ivica Zubac had 17 points and 11 rebounds.
P.J. Washington scored 14 points with some big 3-pointers for the Mavs, going 4 of 8 from deep, and Daniel Gafford had 13 points with several emphatic buckets down low.
Schuyler Dixon, The
