"El Mayo and Guzman Lopez join a growing list of Sinaloa Cartel leaders and associates who the Justice Department is holding accountable in the United States," Garland said.
Zambada faces multiple federal indictments for his alleged role in the cartel and has been on the run from U.S. and Mexican law enforcement for years. His fellow co-founder of the Sinaloa cartel, Joaquín "El Chapo" Guzman, was extradited to the U.S. in 2017 and convicted in 2019 and sentenced to life in prison.
"Today, the FBI and DEA arrested two alleged cartel leaders who have eluded law enforcement for decades. Ismael Mario 'El Mayo' Zambada García and Joaquin Guzman Lopez, son of El Chapo, will now face justice in the United States," Federal Bureau of Investigation Director Christopher Wray said in a statement.
"Garcia and Guzman have allegedly overseen the trafficking of tens of thousands of pounds of cocaine, heroin, methamphetamine, and fentanyl into the U.S. along with related violence. These arrests are an example of the FBI's and our partners commitment to dismantling violent transnational criminal organizations like the Sinaloa Cartel," Wray said.
The circumstances behind Zambada and Guzman Lopez being taken into custody were not immediately clear as of Thursday evening, however, the men were arrested in an operation that ended on U.S. soil.
"El Mayo" thought he was headed to inspect a clandestine Mexican airfield, of which the Sinaloa cartel has many in the country. Instead, according to a Homeland Security Investigations official, a senior ranking member of the cartel tricked him and flew him to El Paso instead.
Upon landing on the tarmac, agents from HSI, along with the FBI arrested "El Mayo" and Guzman.
The HSI official tells ABC News the operation had been planned "for months."
They were placed in handcuffs by FBI agents during an operation culminating at an airstrip not far from El Paso.
"The arrest of Ismael Zambada García, better known as 'El Mayo,' one of the alleged founders and leaders of the Sinaloa Cartel, strikes at the heart of the cartel that is responsible for the majority of drugs, including fentanyl and methamphetamine, killing Americans from coast to coast. El Mayo is one of DEA's most wanted fugitives and he is in custody tonight and will soon face justice in a U.S. court of law," said Drug Enforcement Administration Administrator Anne Milgram.
"Joaquin Guzman Lopez, another alleged leader of the Sinaloa Cartel, and the son of 'El Chapo,' was also arrested today -- his arrest is another enormous blow to the Sinaloa Cartel. In 2017, he and his brothers, the Chapitos, allegedly took control of the Sinaloa Cartel after El Chapo was extradited to the United States. DEA will continue to seek justice for any American life that is lost and will work tirelessly to prevent more needless deaths and pursue those that are responsible," Milgram said.
The U.S. government had offered a $15 million reward for information leading to the arrest and/or conviction of Zambada.
"Too many of our citizens have lost their lives to the scourge of fentanyl," President Joe Biden said in a statement Friday morning. "Too many families have been broken and are suffering because of this destructive drug. My Administration will continue doing everything we can to hold deadly drug traffickers to account and to save American lives."
Ovidio Guzman Lopez had been wanted by U.S. authorities since 2019 and was captured by Mexican armed forces in January 2023 in a small town just outside the city of Culiacán, the capital of the Mexican state of Sinaloa.
